I-Last Order iqala lapho i-nanotechnology kaDesty Nova ivusa u-Alita edolobheni elintantayo laseTiphares. Izimfihlo ezimnyama zedolobha zivezwe ngonya, kepha kubukeka sengathi yingxenye encane yomhlaba eyinkimbinkimbi. Ukuya emkhathini nezinkampani ezindala nezintsha ukuze ufunde kabanzi mayelana nesikhathi asedlule asikhohliwe futhi ngokulinganayo, ukufuna isithandwa sakhe esilahlekile uLou Collins, u-Alita ubambeke empini yangaphakathi kwamaplanethi phakathi kwamandla amakhulu wesistimu yelanga eyayiqokiwe. Endleleni, wenza umfelandawonye nama-Alita Replicas amathathu aseqalile ukuzikholelwa, i-superhacker engathandeki, noNova uqobo lapho engenela iZenith of Things Tournament (ZOTT), umncintiswano wokulwa owawubanjwa njalo eminyakeni eyishumi. Kubandakanya indlela uMhlaba ovele ngayo ebusika obunomthelela omkhulu owasusa iningi lomphakathi kulo lonke ubude bokulandisa, umlando omningi maqondana nokuhlelwa kwe-Battle Angel Alita okwakungadalulwanga ochungechungeni lwangaphambili kukhonjisiwe.
